Journal of the Korean Academy of Child and Adolescent Psychiatry : eISSN 2233-9183 / pISSN 1225-729X

Table. 1.

Table. 1.

Reward pathway

PathwayStructuresReward behaviorAddictive behavior
Ascending (mesolimbic)Ventral tegmental area to nucleus accumbens (shell, core)Desire to repeat a behaviorCraving a drug or behavior
DescendingExtended amygdala to ventral tegmental areaEmotional intensity linked to a behavior or experienceIntoxication linked to a drug, behavior, or experience
Further ascendingCore nucleus accumbens to ventral pallidumPositive reinforcement of behaviorNegative reinforcement of a drug-associated behavior
Shell nucleus accumbens to prefrontal cortex to core nucleus accumbens
InterneuronVentral tegmental areaReinforcing positive reinforcementReinforcement of negative reinforcement of drug use
J Korean Acad Child Adolesc Psychiatry 2017;28:4-13 https://doi.org/10.5765/jkacap.2017.28.1.4
© 2017 J Korean Acad Child Adolesc Psychiatry