Journal of the Korean Academy of Child and Adolescent Psychiatry : eISSN 2233-9183 / pISSN 1225-729X

Table. 1.

Table. 1.

Comparison of demographic characteristics between responders and non-responders to atomoxetine

Responders (n=33) Non-responders (n=32) t or χ2 p
Age, mean (SD) 7.9 (1.6) 7.8 (1.3) 0.524 0.602
Sex, boys, n (%) 28 (84.8) 29 (90.6) 0.708*
FSIQ 94.5 (10.5) 93.8 (12.6) 0.245 0.807
Age of onset, mean (SD) 5.1 (1.5) 5.7 (1.7) -1.359 0.179
Medication dose, mg/kg/day, mean (SD) 0.90 (0.24) 0.87 (0.21) 0.580 0.564
ADHD subtype, n (%) 2.362 0.501
 Inattentive 16 (48.5) 11 (34.4)
 Hyperactive-impulsive 1 (3.0) 2 (6.3)
 Combined 16 (48.5) 18 (56.3)
 NOS 0 (0.0) 1 (3.1)
Comorbid disorder, n (%)
 ODD/CD 5 (15.2) 4 (12.5) 1.000*
 Anxiety disorder 0 (0.0) 2 (6.3) 0.239*
 Tic disorder 5 (15.2) 4 (12.5) 1.000*
 Enuresis 1 (3.0) 0 (0.0) 1.000*

Definition of response to atomoxetine was determined as reduction in ADHD Rating Scale score of more than 50% between pre-treatment and post-treatment (12th week) or less than three in Clinical Global Impression-Improvement scale score at post-treatment (12th week).

using Fisher’s exact test. ADHD: attention-deficit/hyperactivity disorder, CD: conduct disorder, FSIQ: Full-Scale Intelligence Quotient, NOS: not otherwise specified, ODD: oppositional defiant disorder, SD: standard deviation

J Korean Acad Child Adolesc Psychiatry 2019;30:74-82 https://doi.org/10.5765/jkacap.180030
© 2019 J Korean Acad Child Adolesc Psychiatry